Monday, 26 September 2016

Shape-shifting proteins layered like a cake could set Alzheimer’s in motion

New understanding of how amyloid beta proteins gain entry to brain cells may offer up new ...

Scientists have established a rough outline of how Alzheimer's disease takes hold, and bit by bit they are starting to fill in the details. Key players in this process are what are known as amyloid beta proteins which form in clumps, evolve into plaques and cause irreversible damage to the brain. New research has revealed the crafty maneuver that these peptides use to slip past the cell's defenses whereby they first change shape to form stacks of long, flat sheets, a finding that may offer up new opportunities to intervene in the onset of the disease.

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from New Atlas http://ift.tt/2dlB1qL

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