Wednesday, 25 January 2017

Molecule throws roadblock in Alzheimer's path

The antisense oligonucleotide molecule can act like a roadblock in the cycle that produces tau tangles, ...

When it comes to the drama of Alzheimer's disease, the compound in the starring role as the villain is tau. It's a protein that normally helps our neurons function properly, but one that can clump together into plaques that damage brain cells. Now researchers have figured out a way to lower tau levels by throwing a molecular bomb in the works that lead to its creation. Doing so has not only stopped its damaging effects in tests on monkeys and mice, but also reversed some of the damage it wreaks.

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Category: Biology

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