Wednesday, 29 November 2017

First semi-synthetic bacteria with artificial DNA has created an entirely novel protein

These fluorescent cells express a protein encoded by artificial DNA bases

All life on Earth is underpinned by the same DNA building blocks. DNA consists of pairs of four biological compounds known as nucleobases – A, T, C, G (Adenine, Cytosine, Thymine, and Guanine). But what if we created new artificial nucelobases to add to those pairs? Researchers at The Scripps Research Institute are now finding out, having successfully created a semi-synthetic bacteria strain with two new unnatural bases.

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